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Metabolic Lab Tests

Metabolic lab tests test the functional integrity of cellular reactions that can, when malfunctioning have far-reaching effects on the entire body. The metabolism of fats is a prime example of this as well as damage done to the cell itself which can cause premature aging and even cancer.

Several of our lab partners perform Metabolic Lab Tests. Please refer to the About the Labs We Utilize section of the website for links to all of our lab partners and a full list of tests performed by each lab.

For sample reports of some of the lab tests we order please see the links below.

Metabolic Lab Tests

Oxidative Stress Analysis 2.0 - Urine - Genova Diagnostics

The Oxidative Stress Analysis 2.0 is a urine test that evaluates two oxidative tissue damage markers. Oxidative stress underlies many common chronic diseases and balance is crucial for slowing or stopping degenerative processes. The Oxidative Stress Analysis 2.0 can indicate the need for dietary and/or lifestyle modification which can help minimize further oxidative damage

Download a sample report here.

Metabolic Lab Tests

CardioMetabolic Risk Profile - Doctors Data

This advanced test evaluates risk factors for cardiovascular disease (CVD) plus metabolic factors associated with metabolic syndrome and type II diabetes. In addition to the traditional CVD risk factors, the test includes much more clinically sensitive atherogenic lipoprotein sub-species, the primary apolipoproteins, arterial inflammation and the activity of the lipoprotein- associated phospholipase- A2 (PLAC). 

PLAC activity is a very sensitive indicator of active atherogenesis and instability of advanced arterial plaque.


Metabolic syndrome (MetS) is centered around insulin resistance and atherogenic dyslipoproteinemia, and is a risk factor associated with CVD and kidney disease. The test includes cystatin C to better assess glomerular filtration, and 1,5-anhydroglucitol (Glycomark) that is a better indicator of hyperglycemic episodes than HbA1C. The primary adipokines associated with insulin sensitivity and hepatic fatty acid metabolism are also addressed..

Download a sample report here.

Metabolic Lab Tests

Metabolomic Profile - Doctors Data

The Metabolomic Profile provides assessment of the likelihood of Metabolic syndrome in at-risk patients. The Metabolomic Profile evaluates seven biomarkers that may reflect a patient’s risk of developing Metabolic syndrome, which is identified by a cluster of cardiometabolic risk factors, with insulin resistance and adiposity as its central features. Identification of individuals with metabolic syndrome is important due to its association with an increased risk of and type 2 diabetes mellitus, renal damage and coronary heart disease. Early detection of risk for Metabolic Syndrome is very important because associated symptoms may not be evident until it is well advanced.

Download a sample report here.

Metabolic Lab Tests

DetoxiGenomic Profile - Genova Diagnostics

This test evaluates SNPs associated with increased risk of impaired detoxification capacity especially when exposed to environmental toxins. It also identifies individuals potentially susceptible to adverse drug reactions.


SNPs are DNA sequence variations that occur relatively frequently in the general population. They are different from disease mutations, which are very rare. Huntington’s disease is an example of a disease mutation - if you inherit the altered gene, the disease will develop. Certain SNPs may be associated with particular health conditions, but they are not known to directly cause disease. The majority of SNPs affect protein, enzyme or cell receptor structure and function.


SNPs may have subtle but true biological effects. Some SNPs have been correlated with health concerns or disease risk. Often several SNPs need to be present to alter metabolic or biochemical functions in the body. SNP activity and gene expression may often be modified by epigenetic factors (diet, lifestyle, nutrition, toxicant exposures). The effects of SNPs are often cumulative; the expression of a single SNP often depends on the presence or absence of other SNPS.

 

Download a sample report here.

Metabolic Lab Tests

Glucose, Serum - LabCorp

The body uses sugar, also called glucose, to supply the energy it needs to function. People get sugar from their diet and from their body tissues. Insulin is made by the pancreas and affects the outer membrane of cells, making it easy for glucose to move from the blood into the cells. When insulin is active, blood glucose levels fall. Sugar from body tissues is stored in the form of glycogen. When glycogen is active, blood glucose levels rise. Diabetes must be diagnosed as early as possible. If left untreated, it can damage or cause failure of the eyes, kidneys, nerves, heart, blood vessels, and other body organs.

Download a sample report here.

Metabolic Lab Tests

Beta-glucuronidase - Doctors Data

ß-glucuronidase (ß-G) is an enzyme that breaks the tight bond between glucuronic acid and toxins in the intestines. The liver and intestine bind toxins, steroid hormones and some dietary components to glucuronic acid. That is a protective process that limits absorption and enterohepatic resorption of toxins, and enhances excretion.


A high level of activity of ß-G in the gut is not desirable. A low level of ß-G activity is not known to be of any direct clinical consequence. ß -glucuronidase is produced by the intestinal epithelium and certain intestinal bacteria. Observational studies have indicated a correlation between high ß-G activity and certain cancers, but a definitive causal relationship has not been established.


Higher levels of ß-G have been associated with higher circulating estrogens and lower fecal excretion of estrogens in premenopausal women. A potential dietary carcinogen derived from cooked meat and fish induces high ß-G activity and prolongs internal exposure to the toxin in an experimental animal model.

Download a sample report here.

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