Gross Structure of the Adrenal Glands The adrenal glands are on top of each kidney. Each gland has a cortex (outer region) and a medulla (inner region). The cortex secretes glucocorticoids such as cortisol, mineralocorticoids, and small amounts of androgens and estrogens responsible for some secondary sex characteristics. Glucocorticoids raise blood sugar levels by increasing gluconeogenesis (synthesis of glucose from amino acid). This action ensures glucose supplies for the body when it is under stress. Mineralocorticoids such as aldosterone promote sodium (salt) reabsorption by stimulating the kidneys to absorb more sodium from the blood.