Serious harm to the liver caused by drugs, and by the combination of drugs and other substances is an important public health problem. As Americans ingest combinations of prescription and over-the-counter drugs, herbal remedies, dietary supplements and alcohol, the possibilities for harm and liver injury increases. Many of these products are chemicals that are processed and detoxified by the liver. These chemical processes may produce substances that injure liver cells in some people and result in impaired liver functioning. The Toxicity Questionnaire is designed to aid the practitioner in assessing a patient or client's potential need for a liver detoxification Program.