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Some metals are naturally found in the body and are essential to human health. Iron, for example, prevents anemia, and zinc is a cofactor in over 100 enzyme reactions. They normally occur at low concentrations and are known as trace metals. In high doses, they may be toxic to the body or produce deficiencies in other trace metals; for example, high levels of zinc can result in a deficiency of copper, another metal required by the body. A table listing these trace metals can be found here.

Heavy or toxic metals are trace metals with a density at least five times that of water. As such, they are stable elements (meaning they cannot be metabolized by the body) and bio-accumulative (passed up the food chain to humans). These include: mercury, nickel, lead, arsenic, cadmium, aluminum, platinum, and copper (the metallic form versus the ionic form required by the body). Heavy metals have no function in the body and can be highly toxic.

Once liberated into the environment through the air, drinking water, food, or countless human-made chemicals and products, heavy metals are taken into the body via inhalation, ingestion, and skin absorption. If heavy metals enter and accumulate in body tissues faster than the body's detoxification pathways can dispose of them, a gradual buildup of these toxins will occur. High-concentration exposure is not necessary to produce a state of toxicity in the body, as heavy metals accumulate in body tissues and, over time, can reach toxic concentration levels

Heavy metal exposure is not an entirely modern phenomenon: historians have cited the contamination of wine and grape drinks by lead-lined jugs and cooking pots as a contributing factor in the "decline and fall" of the Roman Empire; and the Mad Hatter character in Alice in Wonderland was likely modeled after nineteenth-century hat makers who used mercury to stiffen hat material and frequently became psychotic from mercury toxicity.

Human exposure to heavy metals has risen dramatically in the last 50 years, however, as a result of an exponential increase in the use of heavy metals in industrial processes and products. Today, chronic exposure comes from mercury-amalgam dental fillings, lead in paint and tap water, chemical residues in processed foods, and "personal care" products (cosmetics, shampoo and other hair products, mouthwash, toothpaste, soap). In today's industrial society, there is no escaping exposure to toxic chemicals and metals.

In addition to the hazards at home and outdoors, many occupations involve daily heavy metal exposure. Over 50 professions entail exposure to mercury alone. These include physicians, pharmaceutical workers, any dental occupation, laboratory workers, hairdressers, painters, printers, welders, metalworkers, cosmetic workers, battery makers, engravers, photographers, visual artists, and potters.

In my clinical nutrition practice, when I discuss with patients my concerns regarding heavy metal toxicity, I often get the response, "That isn't a problem for me." Most are astonished to learn that we are all being exposed to and absorbing these harmful substances to some degree in our daily lives. The astonishment turns to alarm when they hear what heavy metals do in the body.

The Effects of Heavy Metal Toxicity Studies confirm that heavy metals can directly influence behavior by impairing mental and neurological function, influencing neurotransmitter production and utilization, and altering numerous metabolic body processes. Systems in which toxic metal elements can induce impairment and dysfunction include the blood and cardiovascular, detoxification pathways (colon, liver, kidneys, skin), endocrine (hormonal), energy production pathways, enzymatic, gastrointestinal, immune, nervous (central and peripheral), reproductive, and urinary.

Breathing heavy metal particles, even at levels well below those considered nontoxic, can have serious health effects. Virtually all aspects of animal and human immune system function are compromised by the inhalation of heavy metal particulates. In addition, toxic metals can increase allergic reactions, cause genetic mutation, compete with "good" trace metals for biochemical bond sites, and act as antibiotics, killing both harmful and beneficial bacteria.

Much of the damage produced by toxic metals stems from the proliferation of oxidative free radicals they cause. A free radical is an energetically unbalanced molecule, composed of an unpaired electron, that "steals" an electron from another molecule to restore its balance. Free radicals result naturally when cell molecules react with oxygen (oxidation) but, with a heavy toxic load or existing antioxidant deficiencies, uncontrolled free-radical production occurs. Unchecked, free radicals can cause tissue damage throughout the body; free-radical damage underlies all degenerative diseases. Antioxidants such as vitamins A, C, and E curtail free-radical activity.

Heavy metals can also increase the acidity of the blood. The body draws calcium from the bones to help restore the proper blood pH. Further, toxic metals set up conditions that lead to inflammation in arteries and tissues, causing more calcium to be drawn to the area as a buffer. The calcium coats the inflamed areas in the blood vessels like a bandage, patching up one problem but creating another, namely the hardening of the artery walls and progressive blockage of the arteries. Without replenishment of calcium, the constant removal of this important mineral from the bones will result in osteoporosis (loss of bone density leading to brittle bones).

Current studies indicate that even minute levels of toxic elements have negative health consequences, however, these vary from person to person. Nutritional status, metabolic rate, the integrity of detoxification pathways (ability to detoxify toxic substances), and the mode and degree of heavy metal exposure all affect how an individual responds. Children and the elderly, whose immune systems are either underdeveloped or age-compromised, are more vulnerable to toxicity.

Common Heavy Metals: Sources and Specific Effects

Aluminum, arsenic, cadmium, lead, mercury, and nickel are the most prevalent heavy metals. The specific sources of exposure, body tissues in which the metal tends to be deposited, and health effects of each metal are identified below.

Sources: Aluminum cookware, aluminum foil, antacids, antiperspirants, baking powder (aluminum containing), buffered aspirin, canned acidic foods, food additives, lipstick, medications and drugs (anti-diarrheal agents, hemorrhoid medications, vaginal douches), processed cheese, "softened" water, and tap water.

Target Organs: Bones, brain, kidneys and stomach.

Signs/Symptoms: Colic, dementia, esophagitis, gastroenteritis, kidney damage, liver dysfunction, loss of appetite, loss of balance, muscle pain, psychosis, shortness of breath, and weakness, Alzheimer's disease, Parkinson's disease, senile and presenile dementia, clumsiness of movements, staggering when walking, and inability to pronounce words properly, behavioral difficulties among school children.

Discussion: Among the patients I see in my practice, the highest aluminum exposure is most frequently due to the chronic consumption of aluminum-containing antacid products and the use of aluminum cookware. Research shows that aluminum builds up in the body over time; thus, the health hazard to older people is greater.

D.R. McLaughlin, M.D., F.R.C.P. (C), professor of physiology and medicine and director of the Centre for Research in Neurodegenerative Diseases at the University of Toronto, states, "Concentrations of aluminum that are toxic to many biochemical processes are found in at least ten human neurological conditions." Recent studies suggest that aluminum contributes to neurological disorders such as Alzheimer's disease, Parkinson's disease, senile and presenile dementia, clumsiness of movements, staggering when walking, and inability to pronounce words properly. Behavioral difficulties among schoolchildren have also been correlated with elevated levels of aluminum and other neurotoxic heavy metals. 66

A disturbing pattern of aluminum accumulation and interference with normal neurological function appears to be supported in the literature. Dyslexic children were shown to have higher levels of aluminum in their hair compared with controls, and other behavioral difficulties in school also correlated with elevated levels of this element.17,18 Urine levels of aluminum are observed to be elevated in people with a history of antacid intake.19 The estimated half-life of aluminum found in the urine is 7.5 hours; however, the excretion kinetics vary according to the form in which the element was present in a worker’s environment.20

There are geographical links between Alzheimer's disease and high aluminum in drinking water. Elevated hair aluminum has been observed in Alzheimer's patients, and some Alzheimer's patients experience stabilization of their symptoms following treatment with the aluminum-chelating agent desferrioxamine. Amyotrophic lateral sclerosis, another neurodegenerative disease, may also be linked to aluminum content of water supplies.

Aluminum is ubiquitous, being the most prevalent heavy metal in the Earth's crust. Sources of exposure may include drinking water (especially from areas exposed to acid rain), aluminum cookware, and aluminum-containing medications such as Maalox.21,22 The health and educational ramifications of these observations are of much current concern.

Sources: Arsenic toxicity has been recognized for centuries, and hair shows significant correlation with intake.58 Arsenic toxicity manifests with various symptoms including macrocytosis and neuropathy. Data show that cereals are a major source of arsenic during infancy and that changes in hair arsenic levels during infancy correspond to the introduction of cereals into the diet.59
Air pollution, antibiotics given to commercial livestock, certain marine plants, chemical processing, coal-fired power plants, defoliants, drinking water, drying agents for cotton, fish, herbicides, insecticides, meats (from commercially raised poultry and cattle), metal ore smelting, pesticides, seafood (fish, mussels, oysters), specialty glass, and wood preservatives. The labels of treated wood and insecticides may be checked for arsenic content.

Target Organs: Most organs of the body, especially the gastrointestinal system, lungs, and skin.

Signs/Symptoms: Abdominal pain, burning of the mouth and throat, cancer (especially lung and skin), coma, diarrhea, nausea, neuritis, peripheral vascular problems, skin lesions, and vascular collapse; macrocytosis and neuropathy.

Lower levels of exposure to inorganic arsenic may cause nausea, vomiting, and diarrhea, decreased production of red and white blood cells, abnormal heart rhythm, blood vessel damage, a "pins and needles" sensation in hands and feet, painful and profuse diarrhea, shock, coma, convulsions and death, irritation, inflammation, ulceration of mucous membranes and skin, kidney damage. Direct skin contact may cause redness and swelling.

Chronic toxic effects are fatigue, loss of energy, G.I. disturbance, nasal septum perforation, ulceration in folds of skin, increased pigmentation of skin, appearance of small "corns" or "warts" on the palms, soles, and torso, exfoliative dermatitis, rashes, muscular paralyses and atrophy, sensory disturbances, visual disturbances and blindness, degeneration of liver (cirrhosis) and kidneys, garlic odor to breath, noncirrhotic portal hypertension.

Discussion: The greatest dangers from chronic arsenic exposure are lung and skin cancers and gradual poisoning, most frequently from living near metal smelting plants or arsenic factories. Arsenic toxicity has been recognized for centuries, and hair shows significant correlation with intake.58

When arsenic enters the environment:

  • It doesn't evaporate.

  • Most arsenic compounds can dissolve in water.

  • It gets into air when contaminated materials are burned.

  • It settles from the air to the ground.

  • It doesn't break down, but can change from one form to another

  • Fish and shellfish build up organic arsenic in their tissues, but most of the arsenic in fish isn't toxic.

Risk of Exposure:

  • Breathing sawdust or burning smoke from wood containing arsenic

  • Breathing workplace air

  • Ingesting contaminated water, soil, or air at waste sites

  • Ingesting contaminated water, soil, or air near areas naturally high in arsenic

  • Inorganic arsenic is a human poison. Organic arsenic is less harmful.

  • High levels of inorganic arsenic in food or water can be fatal. A high level is 60 parts of arsenic per million parts of food or water (60 ppm). Arsenic damages many tissues including nerves (peripheral polyneuropathy, axonal degeneration), stomach and intestines, and skin. Breathing high levels can give you a sore throat and irritated lungs. All arsenicals except arsine act by inhibiting sulfhydryl enzyme systems required for cell metabolism and the potency of action depends on the valency of the arsenic atom. Arsine reacts with haemoglobin to form a very strong haemolytic poison.

Sources: Air pollution, art supplies, bone meal, cigarette smoke, food (coffee, fruits, grains, and vegetables grown in cadmium-laden soil, meats [kidneys, liver, poultry, or refined foods), freshwater fish, fungicides, highway dusts, incinerators, mining, nickel-cadmium batteries, oxide dusts, paints, phosphate fertilizers, power plants, seafood (crab, flounder, mussels, oysters, scallops), sewage sludge, "softened" water, smelting plants, tobacco and tobacco smoke, and welding fumes.

Target Organs: Appetite and pain centers (in brain), brain, heart and blood vessels, kidneys, and lungs.

Signs/Symptoms: Anemia, dry and scaly skin, emphysema, fatigue, hair loss, heart disease, depressed immune system response, hypertension, joint pain, kidney stones or damage, liver dysfunction or damage, loss of appetite, loss of sense of smell, lung cancer, pain in the back and legs, and yellow teeth.

Discussion: Current studies are attempting to determine if cadmium-induced bone and kidney damage can be prevented (or made less likely) by adequate calcium, protein (amino acids), vitamin D, and zinc in the diet.

Cadmium is another toxic metal with a long history of detrimental effects. Hair analysis is useful for evaluating cadmium in smoker and nonsmoker populations of industrially non-exposed urban and rural areas.51 Smoking itself causes significant elevation of toxic element levels in hair, particularly cadmium, lead, and nickel.52 The urine level of cadmium is also a good measure of body stores.53 Under most circumstances, measurement of urine levels is a clinically useful technique. Once the renal threshold has been exceeded, however, urine levels become less trustworthy.54

Cadmium exposure has been associated with hypertension, and studies show that hair levels of hypertensives are higher than controls.55 Hair cadmium has also been shown to be significantly and inversely related to the activity of erythrocyte Na+/K+ ATPase among a group of male smokers. This enzymatic inhibition by cadmium was noted at levels far below toxic levels and may provide additional insight into the link between hypertension and cadmium exposure.56 Cadmium appears to inhibit sulfhydryl-containing enzymes so that relatively low doses depress levels of norepinephrine, serotonin, and acetylcholine.57

To purchase the Hair Tissue Mineral Analysis click

Part 2



What is The Hair Tissue Mineral Analysis? The Toxic Heavy Metals & Why They are a Hazard to Your Health
Sample Hair Tissue Mineral Analysis Report The Trace Metals
The Importance of Minerals to Health How to Take a Hair Sample
Protecting Yourself from Heavy Metals Order the Hair Tissue Mineral Analysis Test
Fluorides - Are You at Risk? Studies Documenting the Effectiveness of the Hair Tissue Mineral Analysis
National Academy of Sciences Backs Stricter Mercury Standards Root Canal Alternatives
Frequently Asked Questions Regarding the Hair Tissue Mineral Analysis Mercury in your fish?
Standard Process Supplements - Parotid 50 Years of Fluoridation - Celebration or Shame?
Water Fluoridation and fluoride in your food can harm you Why Fluorides don't reduce dental caries (cavities)
  Hair Trace Elements and Hypothyroidism   Hair Tissue Mineral Analysis References
  To the Article Index   What YOU can do to help
 

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