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niacin
Also known as: Vitamin B3; Nicotinic Acid

What is it?

Without this VITAMIN, an important member of the B-COMPLEX (sometimes called vitamin B3), the body cannot utilize CARBOHYDRATES, FATS and PROTEINS to provide energy. Thus the amount of niacin the body needs depends on the number of calories consumed. But that's not niacin's only role. It also helps ensure the health and vitality of the skin, digestive tract and nerves. In the early 1900s, when impoverished Southerners subsisted on highly refined corn breads, asylums were full of patients whose dementia was traced to pellagra, a debilitating niacin-deficiency disease. Niacin supplements effected miracle cures and led, ultimately, to the enrichment of cornmeal down South much the way the federal Enrichment Act of 1942 required food processors to restore the IRON, THIAMIN RIBOFLAVIN and niacin lost in the milling of wheat.

In recent years, niacin has been used to treat those with high blood CHOLESTEROL and it can dramatically bring these levels down. But not without side effects, some of them serious. Researchers at two major medical colleges (Virginia and Pennsylvania) studied two dozen people for nine months, gradually upping their niacin dosage from 250 milligrams a day to 3,000 (for healthy adults, the RDA for niacin is 15 to 20 milligrams a day). They learned that although instant-release niacin tablets caused flushing, fatigue and/or skin discoloration, the time-release capsules led to upset stomachs, fatigue and impaired liver function (elsewhere there've been reports of jaundice and liver failure). Given niacin's potentially dangerous side effects, many physicians and nutritionists agree that this B vitamin should no longer be sold over the counter, especially in doses as high as 3,000 milligrams (10 to 20 milligrams are the usual strength). Taken indiscriminately, megadoses can be deadly. A less toxic form of niacin is niacinamide (also called nicotinamide) in which the oxygen-hydrogen (OH) or acid component is replaced by two molecules of hydrogen and one of nitrogen. Niacinamide does not cause the violent "hot flashes" that nicotinic acid does. And it doesn't lower blood cholesterol levels, either.
 

U.S. RDA FOR NIACIN
babies:
birth to 6 months
6 months to 1 year

5 NE per day
6 NE per day
children:
1 to 3 years
4 to 6 years
7 to 10 years

9 NE per day
12 NE per day
13 NE per day
men and boys:
11 to 14 years
15 to 18 years
19 to 50 years
51+ years

17 NE per day
20 NE per day
19 NE per day
15 NE per day
women and girls:
11 to 50 years
51+ years

15 NE per day
13 NE per day
pregnant women 17 NE per day
nursing mothers 20 NE per day

Deficiency Symptoms

Digestive upsets, insomnia, headaches, irritability and, frequently, a sore, swollen, purple-red tongue. More desperate niacin shortfall leads to pellagra: skin and gastrointestinal lesions, inflamed mucous membranes, diarrhea, dementia and death. Now that most cereals, flours, pastas and cornmeals are enriched, full-blown pellagra is history. At least in the United States.

Good Sources

Enriched cereals, meals and flours (plus anything made from them), whole grains, legumes, meat and organ meats, poultry, fish and peanut butter. Besides food sources, the body can obtain niacin by making it from TRYPTOPHAN, an ESSENTIAL AMINO ACID. Nutritionists figure that 60 milligrams of tryptophan equal 1 milligram of niacin. Thus, to calculate the body's niacin requirements, both sources of niacin must be considered. The sum of the two is called the niacin equivalent (NE), and for RDAs today, it is the unit of measurement used.

Precautions

Being water soluble, niacin can leach out in cooking water and be lost unless that water is recycled. Fortunately, niacin isn't destroyed by heat or light like some of the other B vitamins.

Standard Process™ Supplements

Albaplex®, Cataplex® B, B6 Niacinamide, Betacol®, Cardio-Plus®, Cholaplex®, Circuplex®, Diaplex®, Drenamin®, Emphaplex®, Cataplex® G, Gastrex®, Cataplex® GTF, Iplex®, Livaplex®, Min-Chex®, Myo-Plus®, Neuroplex®, Niacinamide B6, Orchex®, Ostarplex®, Rumaplex®, Senaplex®, Vasculin®, Berry StandardBar®, Natural Peanut Butter StandardBar®

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