bilberry
Also known as: Vaccinium myrtillus

What is it?

A close relative of American blueberry, bilberry grows in northern Europe, Canada, and the United States. The ripe berries are used, and the leaves may also contain beneficial compounds.

Bilberry has been used in connection with the following conditions: Night blindness, atherosclerosis, cataracts, diarrhea, varicose veins.

The dried berries and leaves of bilberry have been recommended for a wide variety of conditions, including scurvy, urinary tract infections, kidney stones, and diabetes. Perhaps the most sound historical application is the use of the dried berries to treat diarrhea. Modern research of bilberry was partly based on its use by British World War II pilots, who noticed that their night vision improved when they ate bilberry jam prior to night bombing raids.

Active constituents: Anthocyanosides speed the regeneration of rhodopsin, the purple pigment that is used by the rods in the eye for night vision.1 This makes bilberry a possible first line of defense for those with night blindness.2 Anthocyanosides, the flavonoid complex in bilberries, are potent antioxidants.3 They support normal formation of connective tissue and strengthen capillaries in the body. Anthocyanosides may also improve capillary and venous blood flow. Preliminary human studies conducted in Europe show that bilberry may prevent cataracts,4 and may even treat mild retinopathies (such as macular degeneration and diabetic retinopathy).5 6 Bilberry may also prevent blood vessel thickening due to diabetes.7

Bilberry protects cholesterol from oxidizing in test tubes.8 This may be part of how it helps people with atherosclerosis.

How much is usually taken? Bilberry herbal extract in capsules or tablets standardized to provide 25% anthocyanosides can be taken in the amount of 240–600 mg per day.9 Traditional use is 1–2 ml two times per day in tincture form or 20–60 grams of the fruit daily.

Are there any side effects or interactions? In recommended amounts, no side effects have been reported with bilberry extract. Bilberry is not contraindicated during pregnancy or lactation.

At the time of writing, there were no well-known drug interactions with bilberry.

References:

1. Sala D, Rolando M, et al. Effect of anthocyanosides on visual performance at low illumination. Minerva Oftalmol 1979;21:283–5.

2. Mian E, Curri SB, Lietti A, et al. Anthocyanosides and the walls of microvessels: Further aspects of the mechanism of action of their protective in syndromes due to abnormal capillary fragility. Minerva Med 1977;68:3565–81.

3. Salvayre R, Braquet P, et al. Comparison of the scavenger effect of bilberry anthocyanosides with various flavonoids. Proceed Intl Bioflavonoids Symposium, Munich, 1981, 437–42.

4. Bravetti G. Preventive medical treatment of senile cataract with vitamin E and anthocyanosides: Clinical evaluation. Ann Ottalmol Clin Ocul 1989;115:109 [in Italian].

5. Perossini M, Guidi G, Chiellini S, Siravo D. Diabetic and hypertensive retinopathy therapy with Vaccinium myrtillus anthocyanosides (Tegens): Double-blind placebo-controlled clinical trial. Ann Ottalmol Clin Ocul 1987;12:1173–90 [in Italian].

6. Scharrer A, Ober M. Anthocyanosides in the treatment of retinopathies. Klin Monatsbl Augenheikld Beih 1981;178:386–9.

7. Boniface R, Miskulin M, Robert AM. Pharmacological properties of myrtillus anthocyanosides: Correlation with results of treatment of diabetic microangiopathy. In Flavonoids and Bioflavonoids, L Farkas, M Gabors, FL Kallay, eds. Ireland: Elsevier, 1985, 293–301.

8. Francesca Rasetti M, Caruso D, Galli G, et al. Extracts of Ginkgo biloba L. leaves and Vaccinium myrtillus L. fruits prevent photo induced oxidation of low density lipoprotein cholesterol. Phytomedicine1996/7;3:335–8.

9. Brown DJ. Herbal Prescriptions for Better Health. Rocklin, CA: Prima Publishing, 1996, 41–7.