What is it?

What is going on in the body?

Anaphylaxis is a response to a substance to which a person has become very sensitive. An antibody called IgE causes cells to release a variety of substances called mediators. These mediators are responsible for the allergic reaction. They affect blood vessels, smooth muscle, and inflammatory cells all over the body.

What are the signs and symptoms of the disease?

The symptoms of anaphylaxis may include:

• abdominal distress and diarrhea

• cough

• sneezing

•  nasal congestion

• dizziness

• nausea and vomiting

• severe itching and hives all over the body

• shortness of breath

• swelling of the face or tongue

• swelling over much of the body

• tightness in the chest or throat