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The only hormone secreted into the bloodstream by the
pineal gland. The hormone appears to inhibit numerous endocrine
functions, including the gonadotropic (sex) hormones. Research exists on the
efficacy of melatonin in treating jet lag and certain sleep disorders.
Dosages greater than l milligram have been associated with drowsiness,
headaches, disturbances in sleep/wake cycles and is contraindicated in
those who are on antidepressive medication. It also negatively
influences insulin utilization. Melatonin should not be taken before
first assessing the need as it can create imbalances in other areas of
the endocrine system. |