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The Hair Tissue Mineral Analysis / Studies Documenting the Effectiveness of the Hair Tissue Mineral Analysis

written by Dr. Gary Farr
Last Updated November, 26, 2001

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Page: 2

More studies documenting the use of Hair Tissue Mineral Analysis.

Hair Tissue Mineral Analysis (HTMA) Helpful in Recognizing Mineral Imbalance in Children with Attention Deficit Hyperactive Disorder (ADHD) and Autism
....Kozielec reported in Magnesium Res. 10, 2, 1997 that their investigations concluded that magnesium deficiency occurred more frequently in children with ADHD than in non-affected healthy children. Their study included 116 children whose magnesium status was determined by blood serum, red blood cell and hair analysis. Ninety five percent of the children examined were found to have magnesium deficiency. Hair magnesium was more indicative of deficiency than blood serum or red blood cell analysis.

....A study reported by Wecker, in J. Ment. Def. Res. Part 1, Mar. 1985 found significant differences in the hair trace element concentrations of children with autism and autistic like-conditions compared to control groups. They concluded that their evidence suggests that "hair analysis may have potential use as a diagnostic tool for autism." Our studies at TEI concur with the above findings. Research has shown the effectiveness of magnesium and vitamin B6 therapy in children suffering from autism.

Martineau, J, et al: Long-Term Effects of Combined Vitamin B6 - Magnesium administration in an Autistic Child. Biol. Psyc. 21, 1986.
Relationship of Dental and Oral Pathology to Systemic Illness
.....This article appeared in JAMA 284, 10, 2000. It has been recognized that dental infections are related to chronic cardiovascular disease such as atherosclerosis, however this article points out that dental disease can be related to other systemic illness. The paper sites other investigations showing periodontal disease being related to cerebrovascular ischemia, leading to a 2.6-fold increase in stroke risk.

.....This mechanism can be understood through TMA patterns. An elevated tissue iron to copper (Fe/Cu) ratio is indicative of a bacterial infection. We often see this pattern in individuals who have chronic dental abscesses typically for a year or longer. During a bacterial infection, tissue Cu levels decrease while tissue iron levels increase. This sets up an abnormal cellular chemistry contributing to a number of disturbances. Fe is well known to be a contributor to lipid peroxide and hydroxyl radical formation while Cu deficiency is associated with a reduction in Cu, Zn superoxide dismutase activity. Therefore, the increase in the tissue Fe/Cu ratio leads to mitochondrial disorders, and extensive free radical damage to tissues and particular lipid tissues. A review of laboratory results from our database of patients who suffered from stroke revealed that over 75 % had low tissue Cu levels. Cu deficiency is commonly found in individuals with coronary disease as well.

Following the Recovery of Naso-Pharyngeal Cancer (NPC) Patients by Trace Elements in Hair Using Statistical Pattern Recognition Methods.
.....This study by Lueng, et al. Appeared in Biological Trace Element Research, Vol. 62, 1998. The study followed the recovery of patients with NPC using hair mineral analysis prior to and after 3 and 6 months of treatment compared to a control group. After statistical pattern recognition methods they found that the follow-up hair mineral patterns reflected the different recovery phases of the NPC patients. This study demonstrates that mineral imbalances are found in disease states and that improvement in patient s condition is reflected in improved hair mineral concentrations.

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