Women's Conditions / The Vaginosis Profile

submitted by Dr. Gary Farr Last Updated June, 24, 2004

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Great Smokies Diagnostic Laboratory offers a very comprehensive Vaginosis Profile to find the cause of vaginal symptoms.

Recurrent or chronic vaginitis is not only a source of great discomfort to many women, but also a potential threat to a woman's reproductive health and the well-being of her fetus during pregnancy. The condition is coming to be recognized as capable of increasing a woman's risk for acquiring sexually transmitted disease, including HIV. Because of the importance of specific identification and treatment tailored to the cause, quality assessment is especially important. The possible causes are many, and may be tricky to ascertain without advanced testing.

The Vaginosis Profile from Great Smokies Diagnostic Laboratory is one of the most comprehensive evaluations available. It features microscopy for every sort of organism by trained and experienced technicians with an advanced DNA probe for the most common causes of the condition. With a rapid, semiautomated DNA probe test to definitively identify clinically significant levels of Gardnerella, and Trichomonas, detection rates for these organisms can reach levels of 90% and greater in properly transported specimens.

Vaginal fluid is microscopically examined not only for common causes of vaginitis, but also for the presence of white blood cells. Both yeast and bacterial cultures reveal the presence of possibly pathogenic organisms. In an increasing number of women, signs of severe inflammation may be caused by several "survivor" micro-organisms which have become resistant to repeated therapy.

A sensitivity panel accompanies reports which demonstrate a possible pathogen, whether bacterial, parasitic, or fungal, so that appropriate agents may be selected for treatment. A bacterial culture also demonstrates the presence and concentration of Lactobacilli, the protective bacteria which can be so easily eradicated with the use of oral antibiotics. Cell lysis is noted, if present, which may occur when an overgrowth of Lactobacilli renders the vagina too acidic.

What You Should Know

What is measured on this profile?
Protective bacteria, additional bacteria, yeast overgrowth, and cytolysis of the cells. This is accomplished through cultures and a microscopic exam.

What is cell cytolysis?
A condition in which the vagina is too acidic from Lactobacillus overgrowth.

Are Trichomonas or Gardnerella reported?
Gardnerella is detected via the demonstration of clue cells (bacterial adherence to epithelial cells), and reported if found. The best way to detect the Trichomonas is through examination of a fresh specimen, usually in the doctor's office.

Can I do the test if I'm menstruating?
No, it's important that you wait until you have finished menstruating.

Can I douche prior to the test?
No, douching will interfere with the vaginal flora.

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